In recent years, there have been two occasions on which the technology has really changed the way I take pictures, the first was the IS system with Canon, or Image Stabilisation allowing hand-held shot that were just not possible before (such as shooting from an helicopter from instance or wherever the use of a tripod is not convenient or permitted, eg: church) and digital has brought the ability to change ISO setting on the fly. I have to say that I have been really impressed with the capacity of the 5D to maintain noise levels at a minimum, I am now happily shooting inside most churches without a flash at ISO 1600, it really does bring depth to the pictures.
Something that was just not possible with previous eos camera (or Nikon for that matter) when shots taken at more than ISO800 were barely usable.
Of course I will still be shooting some 3200ISO B&W as well, just because I love it.
Nico